Management of Feline Orofacial Pain Syndrome (FOPS) – with Interventional Pain techniques 

cat after FOPS from NDSR

Feline Orofacial Pain Syndrome (FOPS) is a condition associated with episodes of severe oral discomfort. Pain in FOPS often recurs and is poorly responsive to first-line treatments. 

Affected cats often display exaggerated licking and chewing movements, especially after eating or grooming. Pawing at the mouth is common, and more severe cases will present with tongue and face mutilation.   

Some cats are in continuous discomfort, and the nature of their pain can lead to a reluctance to eat or even become anorexic. Breeds that are more susceptible to this disease include Burmese Siamese, Tonkinese and Burmilla. While cats of any age can be affected, many will first show signs when erupting permanent teeth.  

As no definite diagnosis for FOPS is available, it will be crucial to exclude other possible causes associated with orofacial pain. These may include dental and periodontal disease, oral lesions and a lack of response to initial treatments, particularly in predisposed breeds.  

Additionally, it is essential to assess mental status, orofacial sensation, vestibular signs, and the presence of paresis or any other neurological alterations that could be linked to other neuropathies or neurological disorders.  

While the pain associated with FOPS is often triggered or exacerbated by dental disease and further exacerbated by environmental factors, it typically responds poorly to most first-line treatments. Consequently, the quality of life for many affected cats is significantly impacted, forcing owners to make difficult decisions. 

FOPS is a neuropathic pain disorder that can be considered analogous to human trigeminal neuralgia. Similar to human medicine, chronic orofacial pain associated with FOPS can be effectively alleviated with minimally invasive Interventional Analgesic Procedures (IAP), especially when oral medications fail to relive the pain. 

At NDSR, and as part of a multimodal analgesic approach, we have experience with a variety of minimally invasive IAP aimed at alleviating the pain in cats with FOPS. By means of ultrasound, we are able to guide injections and other treatment modalities, which in turn allow us to identify and treat the specific source of pain.  

References : 

– Epstein ME (2020) Feline Neuropathic Pain. Vet Clin North Am Small Anim Pract 50 (4), 789-809 

– Rusbridge C, Heath S (2016) Feline Orofacial Pain Syndrome. In Feline Behavioral Health and Welfare (1st edn). Rondan I, Health S (eds). Elsevier, USA. pp 213-226 

– Deer TR, Leong MS, Buvanendran A, Panchal KSJ (2015) Treatment of Chronic Pain by Interventional Approaches. American Academy of Pain Medicine, Springer, USA. 

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Anaesthesia and Analgesia Team

Our Anaesthesia and Analgesia Team offer a caring, multi-disciplinary approach to all medical and surgical conditions.

Maria Angeles Jimenez Lozano

CertVA DipECVAA MRCVS

Aurora Zoff

DVM(Hons) CertAVP(VA) Dip. ACVAA Dip. ECVAA MRCVS

Rui Pinelas

MVM DipECVAA MRCVS

Jodie Hughes

BVSc CertAVP(VA) DipECVAA MRCVS

Roger Medina Serra

DVM MVetMed DipECVAA MRCVS

Luisa Viterbo

DVM MRCVS

Carlos Millan